Volume 19, Number 3 / July, 2012

Author Disclosure Summary

Special Online Issue Dedicated to Translation Research and Biomarkers: Author Disclosure Summary

View abstract | View full article HTML | View full article PDF

Translational Research and Biomarkers

Single Nucleotide Polymorphisms and Haplotypes of MMP-14 are Associated with the Risk and Pathological Development of Oral Cancer

Chia-Jui Weng PhD, Mu-Kuan Chen MD, Chiao-Wen Lin MS, Tsung-Te Chung MD, Shun-Fa Yang PhD
View abstract | View full article HTML | View full article PDF

Integrated Analysis of Prognostic Gene Expression Profiles from Hepatitis B Virus-Positive Hepatocellular Carcinoma and Adjacent Liver Tissue

Bu-Yeo Kim PhD, Kyung-Suk Suh MD, PhD, Je-Geun Lee PhD, Seon Rang Woo PhD, In-Chul Park PhD,, Sun-Hoo Park MD, PhD, Chul Ju Han MD, PhD, Sang-Bum Kim MD, PhD, Sook-Hyang Jeong MD, PhD, Young Il Yeom PhD, Suk-Jin Yang PhD, Chang-Min Kim MD, PhD, Su Jin Cho PhD, Young Do Yoo PhD, Myung-Haing Cho PhD, Ja June Jang MD, PhD, Dong Wook Choi MD, PhD, Kee-Ho Lee PhD
View abstract | View full article HTML | View full article PDF

CXCR4 Expression Predicts Patient Outcome and Recurrence Patterns after Hepatic Resection for Colorectal Liver Metastases

Adam C. Yopp MD, Jinru Shia MD, Jean M. Butte MD, Peter J. Allen MD, Yuman Fong MD, William R. Jarnagin MD, Ronald P. DeMatteo MD, Michael I. D’Angelica MD
View abstract | View full article HTML | View full article PDF

Impact of KRAS and EGFR Gene Mutations on Recurrence and Survival in Patients with Surgically Resected Lung Adenocarcinomas

Makoto Sonobe MD, PhD, Masashi Kobayashi MD, Masashi Ishikawa MD, Ryutaro Kikuchi MD, Ei Nakayama MD, Tsuyoshi Takahashi MD, PhD, Toshi Menju MD, Kazumasa Takenaka MD, PhD, Ryo Miyahara MD, PhD, Cheng-Long Huang MD, PhD, Kenichi Okubo MD, PhD, Toru Bando MD, PhD, Hiroshi Date MD, PhD
View abstract | View full article HTML | View full article PDF

Role of the Hypoxia-Related Gene, JMJD1A, in Hepatocellular Carcinoma: Clinical Impact on Recurrence after Hepatic Resection

Daisaku Yamada MD, Shogo Kobayashi MD, PhD, Hirofumi Yamamoto MD, PhD, Yoshito Tomimaru MD, Takehiro Noda MD, PhD, Mamoru Uemura MD, PhD, Hiroshi Wada MD, PhD, Shigeru Marubashi MD, PhD, Hidetoshi Eguchi MD, PhD, Masahiro Tanemura MD, PhD, Yuichiro Doki MD, PhD, Masaki Mori MD, PhD, Hiroaki Nagano MD, PhD
View abstract | View full article HTML | View full article PDF

Different Expression Patterns of CEACAM1 and its Impacts on Angiogenesis in Gastric Nonneoplastic and Neoplastic Lesions

Jian-Qiang Guo MD, Wei-Hua Yu MD, Hong-Juan Wang MD, Bin Liu MD, Kong-Xi Zhu MD, Qing-Hui Zhang MD, Ting-Guo Zhang MD, Wei-Hua Xu MD, Hong-Bo Wang MD, Hong-Li Wu MD, Cheng-Jun Zhou MD
View abstract | View full article HTML | View full article PDF

The Significance of MMP-9 Over MMP-2 in HCC Invasiveness and Recurrence of Hepatocellular Carcinoma After Curative Resection

Rongxin Chen MD, PhD, Jiefeng Cui MD, PhD, Changde Xu MD, PhD, Tongchun Xue MD, PhD, Kun Guo MD, PhD, Dongmei Gao BMSC, Yinkun Liu MD, PhD, Shenglong Ye MD, PhD, Zhenggang Ren MD, PhD
View abstract | View full article HTML | View full article PDF

Prognostic Significance of TWEAK Expression in Colorectal Cancer and Effect of Its Inhibition on Invasion

Been-Ren Lin PhD, MD, Miao-Tzu Huang PhD, Szu-Ta Chen MD, Yung-Ming Jeng PhD, MD, Yue-Ju Li MS, Jin-Tung Liang PhD, MD, Po-Huang Lee PhD, MD, King-Jen Chang PhD, MD, Cheng-Chi Chang PhD
View abstract | View full article HTML | View full article PDF

Molecular Profiling of Direct Xenograft Tumors Established from Human Pancreatic Adenocarcinoma After Neoadjuvant Therapy

Michael P. Kim MD, Mark J. Truty MD, Woonyoung Choi PhD, Ya’an Kang MD, Xavier Chopin-Lally MD, Gary E. Gallick PhD, Huamin Wang MD, David J. McConkey PhD, Rosa Hwang MD, Craig Logsdon PhD, James Abbruzzesse MD, Jason B. Fleming MD
View abstract | View full article HTML | View full article PDF

Overexpression of Renal Tumor Antigen Is Associated with Tumor Invasion and Poor Prognosis of Hepatocellular Carcinoma

Hyung Jin Cha BS, Jongmin Kim PhD, Sun Mi Hong BS, Seok Joo Hong PhD, Jun Ho Park BS, Eung-Sam Kim MS, Hee-Jung Wang MD, Yoon Jung Choi MD, In-Gu Do MD, Jae Won Joh MD, Dae Shick Kim MD, PhD, Kwan Yong Choi PhD
View abstract | View full article HTML | View full article PDF

Expression of IGF1R Is Associated with Tumor Differentiation and Survival in Patients with Lung Adenocarcinoma

Ryutaro Kikuchi MD, Makoto Sonobe MD, PhD, Masashi Kobayashi MD, Masashi Ishikawa MD, Jiro Kitamura MD, Ei Nakayama MD, Toshi Menju MD, Ryo Miyahara MD, PhD, Cheng-long Huang MD, PhD, Hiroshi Date MD, PhD
View abstract | View full article HTML | View full article PDF

Inhibition of Heat Shock Protein Response Enhances PS-341-Mediated Glioma Cell Death

Yaohua Liu MD, PhD, Tianhu Zheng PhD, Shiguang Zhao MD, PhD, Huailei Liu MD, Dayong Han MD, Yunbo Zhen MD, PhD, Dongxiao Xu MD, Yu Wang MD, Hongyu Yang MD, Guang Zhang MD, Chunlei Wang MD, Jianing Wu MD, Yuanzhu Ye MD
View abstract | View full article HTML | View full article PDF

Clinical Significance of Molecular Detection of Matrix metalloproteinase-1 in Bone Marrow and Peripheral Blood in Patients with Gastric Cancer

Yoshimasa Kosaka MD, PhD, Koshi Mimori MD, PhD, Takeo Fukagawa MD, PhD, Kenji Ishikawa MD, Tsuyoshi Etoh MD, PhD, Hitoshi Katai MD, PhD, Takeshi Sano MD, PhD, Masahiko Watanabe MD, PhD, Mitsuru Sasako MD, PhD, Masaki Mori MD, PhD, FACS
View abstract | View full article HTML | View full article PDF

Clinicopathological Analysis of β-catenin and Axin-1 in Solid Pseudopapillary Neoplasms of the Pancreas

Shih-Chiang Huang, Kwai-Fong Ng, Ta-Sen Yeh, Hao-Cheng Chang, Chia-Yi Su, Tse-Ching Chen
View abstract | View full article HTML | View full article PDF

Recurrence and Poor Prognosis Following Resection of Small Hepatitis B-Related Hepatocellular Carcinoma Lesions Are Associated with Aberrant Tumor Expression Profiles of Glypican 3 and Osteopontin

Ming-Chin Yu MD, Yun-Shien Lee PhD, Sey-En Lin MD, PhD, Hsiang-Yao Wu MS, Tse-Ching Chen MD, PhD, Wei-Chen Lee MD, Miin-Fu Chen MD, Chi-Neu Tsai PhD
View abstract | View full article HTML | View full article PDF

High Expression of Delta-Like Ligand 4 Predicts Poor Prognosis After Curative Resection for Pancreatic Cancer

Hai-Tao Chen MD, Quan-Cai Cai MD, Jian-Ming Zheng MD, Xiao-Hua Man MD, Hui Jiang MD, Bin Song MD, Gang Jin MD, Wei Zhu MD, Zhao-Shen Li MD
View abstract | View full article HTML | View full article PDF

Novel C-Terminal Hsp90 Inhibitor for Head and Neck Squamous Cell Cancer (HNSCC) with in vivo Efficacy and Improved Toxicity Profiles Compared with Standard Agents

Stephanie M. Cohen MD, Ridhwi Mukerji MD, Abbas K. Samadi PhD, Huiping Zhao PhD, Brian S. J. Blagg PhD, Mark S. Cohen MD, FACS
View abstract | View full article HTML | View full article PDF

Claudin-4 Expression Predicts Survival in Pancreatic Ductal Adenocarcinoma

Kosuke Tsutsumi MD, PhD, Norihiro Sato MD, PhD, Reiko Tanabe MD, Kazuhiro Mizumoto MD, PhD, Katsuya Morimatsu MD, Tadashi Kayashima MD, Hayato Fujita MD, PhD, Kenoki Ohuchida MD, PhD, Takao Ohtsuka MD, PhD, Shunichi Takahata MD, PhD, Masafumi Nakamura MD, PhD, Masao Tanaka MD, PhD, FACS
View abstract | View full article HTML | View full article PDF

Axl Is a Prognostic Marker in Oral Squamous Cell Carcinoma

Chien-Hsing Lee MD, PHD, Ching-Yu Yen DDS, Shyun-Yeu Liu DDS, Chi-Kang Chen MD, Chi-Fu Chiang MD, Shine-Gwo Shiah PHD, Pei-Hsuan Chen DDS, Yi-Shing Shieh DDS, PHD
View abstract | View full article HTML | View full article PDF

Inverse Association between miR-194 Expression and Tumor Invasion in Gastric Cancer

Yongxi Song MD, Feng Zhao MD, Zhenning Wang MD, PhD, Zhuangkai Liu MD, Yeunpo Chiang MD, Yingying Xu MD, PhD, Peng Gao MD, Huimian Xu MD, PhD
View abstract | View full article HTML | View full article PDF

Soluble CXCL16 in Preoperative Serum is a Novel Prognostic Marker and Predicts Recurrence of Liver Metastases in Colorectal Cancer Patients

Kohei Matsushita, Yuji Toiyama, Koji Tanaka, Susumu Saigusa, Junichiro Hiro, Keiichi Uchida, Yasuhiro Inoue, Masato Kusunoki
View abstract | View full article HTML | View full article PDF

Association of FANCC and PTCH1 with the Development of Early Dysplastic Lesions of the Head and Neck

Amlan Ghosh PhD, Susmita Ghosh PhD, Guru Prasad Maiti MSc, Sudeshna Mukherjee MSc, Nupur Mukherjee MSc, Jayanta Chakraborty MS, Anup Roy MD, Susanta Roychoudhury PhD, C. K. Panda PhD
View abstract | View full article HTML | View full article PDF

Increased CD13 Expression Reduces Reactive Oxygen Species, Promoting Survival of Liver Cancer Stem Cells via an Epithelial–Mesenchymal Transition-like Phenomenon

Ho Min Kim, Naotsugu Haraguchi, Hideshi Ishii, Masahisa Ohkuma, Miho Okano, Koshi Mimori, Hidetoshi Eguchi, Hirofumi Yamamoto, Hiroaki Nagano, Mitsugu Sekimoto, Yuichiro Doki, Masaki Mori
View abstract | View full article HTML | View full article PDF

Prognostic Significance of NBS1 and Snail Expression in Esophageal Squamous Cell Carcinoma

Kuang-Tai Kuo MD, Teh-Ying Chou MD, Han-Shui Hsu MD, Wen-Liang Chen PhD, Liang-Shun Wang MD
View abstract | View full article HTML | View full article PDF

Immunohistochemical Analysis of Human Equilibrative Nucleoside Transporter-1 (hENT1) Predicts Survival in Resected Pancreatic Cancer Patients Treated with Adjuvant Gemcitabine Monotherapy

Soichiro Morinaga MD PhD, Yoshiyasu Nakamura, Takuo Watanabe MD, Hiroshi Mikayama MD, Hiroshi Tamagawa MD, Naoto Yamamoto MD, Manabu Shiozawa MD PhD, Makoto Akaike MD PhD, Shinnichi Ohkawa MD PhD, Yoichi Kameda MD PhD, Yohei Miyagi MD PhD
View abstract | View full article HTML | View full article PDF

Carcinogenesis of Intraductal Papillary Mucinous Neoplasm of the Pancreas: Loss of MicroRNA-101 Promotes Overexpression of Histone Methyltransferase EZH2

Osamu Nakahara MD, Hiroshi Takamori MD, Masaaki Iwatsuki MD, Yoshifumi Baba MD, Yasuo Sakamoto MD, Hiroshi Tanaka MD, Akira Chikamoto MD, Kei Horino MD, Toru Beppu MD, Keiichiro Kanemitsu MD, Yumi Honda MD, Ken-ichi Iyama MD, Hideo Baba MD
View abstract | View full article HTML | View full article PDF

Silencing of Glucose-Regulated Protein 78 (GRP78) Enhances Cell Migration Through the Upregulation of Vimentin in Hepatocellular Carcinoma Cells

Po-Li Wei MD, PhD, Li-Jen Kuo MD, Weu Wang MD, Feng-Yen Lin PhD, Hui-Hsiung Liu MD, PhD, Tseng How PhD, Yuan-Soon Ho PhD, Ming-Te Huang MD, Chih-Hsiung Wu MD, PhD, Yu-Jia Chang PhD
View abstract | View full article HTML | View full article PDF

NNK Enhances Cell Migration through α7-nicotinic Acetylcholine Receptor Accompanied by Increased of Fibronectin Expression in Gastric Cancer

Weu Wang MD, Hung Chin-Sheng MD, Li-Jen Kuo MD, Po-Li Wei MD, Yung-Chang Lien MD, Feng-Yen Lin PhD, Hui-Hsiung Liu MD, PhD, Yuan-Soon Ho PhD, Chih-Hsiung Wu MD, Yu-Jia Chang PhD
View abstract | View full article HTML | View full article PDF

TNFAIP8 Overexpression: Clinical Relevance to Esophageal Squamous Cell Carcinoma

Yuni Elsa Hadisaputri Pharm.D, Tatsuya Miyazaki MD, PhD, Shigemasa Suzuki MD, Takehiko Yokobori MD, PhD, Tsutomu Kobayashi MD, PhD, Naritaka Tanaka MD, PhD, Takanori Inose MD, PhD, Makoto Sohda MD, PhD, Hiroyuki Kuwano MD, PhD
View abstract | View full article HTML | View full article PDF

Cortical and Subventricular Zone Glioblastoma-Derived Stem-Like Cells Display Different Molecular Profiles and Differential In Vitro and In Vivo Properties

Aurélie Tchoghandjian PhD, Nathalie Baeza-Kallee PhD, Christophe Beclin PhD, Philippe Metellus PhD, Carole Colin PhD, François Ducray PhD, José Adélaïde PhD, Geneviève Rougon PhD, Dominique Figarella-Branger PhD
View abstract | View full article HTML | View full article PDF

A Pathway-Based Approach to Identify Molecular Biomarkers in Cancer

Marvaretta Stevenson MD, Anil Potti MD
View abstract | View full article HTML | View full article PDF

Survivin T9809C, an SNP Located in 3′-UTR, Displays a Correlation with the Risk and Clinicopathological Development of Hepatocellular Carcinoma

Yih-Shou Hsieh PhD, Chiung-Man Tsai MS, Chao-Bin Yeh MD, PhD, Shun-Fa Yang PhD, Yi-Hsien Hsieh PhD, Chia-Jui Weng PhD
View abstract | View full article HTML | View full article PDF

Transient but Not Stable ZEB1 Knockdown Dramatically Inhibits Growth of Malignant Pleural Mesothelioma Cells

Mihoko Horio MD, Mitsuo Sato MD, PhD, Yoshihiro Takeyama MD, PhD, Momen Elshazley MD, MSc, Ryo Yamashita MD, Tetsunari Hase MD, Kenya Yoshida MD, Noriyasu Usami MD, PhD, Kohei Yokoi MD, PhD, Yoshitaka Sekido MD, PhD, Masashi Kondo MD, PhD, Shinya Toyokuni MD, PhD, Adi F. Gazdar MD, John D. Minna MD, Yoshinori Hasegawa MD, PhD
View abstract | View full article HTML | View full article PDF

Combined Analysis of Dihydropyrimidine Dehydrogenase and Human Equilibrative Nucleoside Transporter 1 Expression Predicts Survival of Pancreatic Carcinoma Patients Treated with Adjuvant Gemcitabine Plus S-1 Chemotherapy after Surgical Resection

Naru Kondo MD, Yoshiaki Murakami MD, Kenichiro Uemura MD, Takeshi Sudo MD, Yasushi Hashimoto MD, Akira Nakashima MD, Taijiro Sueda MD
View abstract | View full article HTML | View full article PDF

MicroRNA-200b Regulates Cell Proliferation, Invasion, and Migration by Directly Targeting ZEB2 in Gastric Carcinoma

Junji Kurashige MD, Hidenobu Kamohara MD, PhD, Masayuki Watanabe MD, PhD, Yukiharu Hiyoshi MD, PhD, Masaaki Iwatsuki MD, PhD, Youhei Tanaka MD, Koichi Kinoshita MD, Seiya Saito MD, Yoshifumi Baba MD, Hideo Baba MD, PhD, FACS
View abstract | View full article HTML | View full article PDF

A Novel Genetically Modified Oncolytic Vaccinia Virus in Experimental Models is Effective Against a Wide Range of Human Cancers

Dana Haddad MD, Nanhai Chen PhD, Qian Zhang MD, PhD, Chun-Hao Chen MD, Yong A. Yu PhD, Lorena Gonzalez MD, Jason Aguilar MS, Pingdong Li MD, Joyce Wong MD, Aladar A. Szalay PhD, Yuman Fong MD
View abstract | View full article HTML | View full article PDF

K-ras Mutation is Strongly Associated with Perineural Invasion and Represents an Independent Prognostic Factor of Intrahepatic Cholangiocarcinoma after Hepatectomy

Tse-Ching Chen MD,PhD, Yi-Yin Jan MD, Ta-Sen Yeh MD, PhD
View abstract | View full article HTML | View full article PDF