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Annals of Surgical Oncology

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Long-Term Outcomes of Robot-Assisted Surgery in Patients with Colorectal Cancer

Ismail Pinar MD, Tina Fransgaard MD, Lau C. Thygesen PhD, Ismail Gögenur DMSc
Colorectal Cancer
Volume 25, Issue 13 / December , 2018



Robotic technology has been proven to be a safe alternative to conventional laparoscopy with regards to the peri- and postoperative clinical outcomes. Oncological outcomes have been scarcely examined. The purpose of this study was to examine the disease-free survival in relation to the two surgical approaches: robot-assisted surgery and conventional laparoscopy. In addition, all-cause mortality and recurrence-free survival were investigated.


Between January 2010 and December 2015, patients, undergoing either laparoscopic or robot-assisted elective, curative-intended surgery for colorectal cancer were included.


A total of 9184 patients underwent surgery in the study period: 5978 patients for colon cancer and 3206 patients for rectal cancer. Among patients with colon cancer, 331 patients (5.5%) underwent robot-assisted surgery, and 449 patients (14.0%) underwent robot-assisted surgery in the rectal cancer group. In the adjusted analyses, the hazard ratio (HR) for disease-free survival, for patients with colon cancer was 0.91 [95% confidence interval (CI) 0.71–1.18]. For patients with rectal cancer, the adjusted HR was 0.83 (95% CI 0.65–1.06). No difference in all-cause mortality and recurrence-free survival were observed.


The study demonstrated comparable rates of disease-free survival, all-cause mortality, and recurrence-free survival when comparing robot-assisted surgery with conventional laparoscopy in patients with colorectal cancer.

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